N-Clomiphene - 90mg/3ml
- Stock: In Stock
- Brand: Nordic Peptides
- Model: N-Clomiphene
Enclomiphene is the purified E-isomer of Clomiphene Citrate (a selective estrogen receptor modulator – SERM) that reactivates your HPTA and boosts endogenous testosterone by blocking estrogenic feedback at the hypothalamus. Compared to the mixed-isomer clomiphene, this eutomer delivers a cleaner, shorter-acting, fertility-friendly hormonal response for performance, recovery, and wellness.
Peptide / Compound Profile
- Peptide Name: Enclomiphene (Enclomiphene Citrate)
- CAS Number: 7599-79-3 (citrate salt)
- Molecular Formula: C32H36ClNO8 (citrate salt)
- Main Function: Restores endogenous T via ↑ LH/FSH (hypothalamic ER antagonism)
- Mechanism of Action: SERM antagonism at the hypothalamus → removes estrogen negative feedback → pituitary releases LH & FSH → testes increase natural testosterone while preserving spermatogenesis.
Key Features & Benefits
- Elevates LH & FSH → natural testosterone increase
- Maintains fertility / sperm counts (vs. exogenous testosterone)
- Shorter-acting than Z-isomer → cleaner control & less buildup
- Helps rebalance estrogen-dominant states
- Non-steroidal; supports energy, mood, libido & recovery
Use Case — Who Benefits Most
- Research on secondary hypogonadism / HPTA restoration
- Post-suppression recovery models where fertility preservation matters
- Protocols targeting hormonal balance without external androgens
Effects on Key Areas
- Blood sugar / appetite: Neutral in clinical reports (focus is gonadotropins / testosterone)
- Muscle & performance: Improved drive & recovery through higher endogenous T (indirect)
- Weight / fat loss: May aid body composition through restored T (supportive, not primary)
- Libido / mood / sleep: Often improve as testosterone normalizes
- Fertility: Maintained vs. reductions seen with topical testosterone comparators
Recommended Dosage & Administration
Recommended protocol: 8–10 units once daily.
1 unit = 300 mcg.
1 pen contains: 300 units.
Adjust the pen’s dosing dial by rotating it (one unit corresponds to one division on the dial), and inject it into the abdominal area. After injecting, wait for 10 seconds before removing the needle. Rotate the injection site with each use.
Treatment duration depends on individual needs and goals.
Administration Tips
- Timing: Once daily, consistently (morning or evening)
- Cycle management: Evaluate hormonal markers around week 4 to guide continuation
- Stacking: Avoid agents that suppress LH / FSH if HPTA restoration is the goal – consistent with SERM MOA
What Is Enclomiphene?
Enclomiphene is the E-isomer of Clomiphene; Zuclomiphene is the Z-isomer. Standard Clomiphene is approximately 62% E : 38% Z. The Z-isomer is more estrogenic and long-lived (detectable for > 1 month), while Enclomiphene clears faster and drives the desired LH/FSH response. Purifying Enclomiphene removes estrogenic baggage and improves hormonal control.
Benefits
- HPTA Reactivation: blocks ER feedback → ↑ LH/FSH → ↑ Testosterone
- Fertility-Friendly: maintains sperm counts vs. testosterone gel comparators
- Clean Hormonal Profile: shorter-acting than Z-isomer → less accumulation
- Performance & Recovery: higher natural T supports strength and recovery
- Wellness: enhanced mood, motivation, and libido alongside T restoration
Clinical Trials & Research
- BJU International (2016): Oral Enclomiphene raised testosterone and maintained sperm counts vs. testosterone gel (which reduced spermatogenesis).
- Reviews & Expert Opinion: Enclomiphene increases LH/FSH and TT without harming semen parameters; promoted as “restoration instead of replacement.”
Applications in Sports & Fitness
- Accelerated recovery after hormonal suppression models
- Tendon / joint support indirectly via normalized androgen levels
- Endurance & training drive through better energy and mood
- Body composition support associated with restored physiological testosterone
Sports outcomes are secondary to endocrine action; results vary by protocol and subject.
Possible Side Effects
Generally well-tolerated. Mild, temporary effects may include:
- Mood fluctuations or irritability
- Headache or pressure sensation
- Temporary libido changes
Consistent cycle length and steady dosing help minimize events. No adverse impact on sperm parameters was observed vs. testosterone gel in clinical trials.
FAQs
What is Enclomiphene?
It is the active E-isomer of Clomiphene that boosts LH/FSH to restore natural testosterone.
How does it differ from Clomiphene?
Clomiphene is a 62 : 38 E : Z mix; the Z-isomer is more estrogenic and long-lived. Enclomiphene isolates the desired activity for cleaner control.
What’s the research-supported dosing?
Human trials used oral tablets 6.25–25 mg/day (typically 12.5–25 mg/day) for 4–8 weeks with testosterone rising within 2–4 weeks and sperm counts maintained.
Is there an injectable “pen/unit” format?
No peer-reviewed human data confirm a subcutaneous format or unit-based dosing; literature supports oral Enclomiphene Citrate only.
Is it approved?
The EMA refused approval in 2018; development for marketing was discontinued in multiple regions. Use research-appropriate positioning.
Ready to restore natural testosterone, protect fertility, and power up performance?
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